Are Dermal Fillers and Injectables the Same? What Are the Three Main Dermal Fillers Used by Doctors?

Are Dermal Fillers and Injectables the Same? What Are the Three Main Dermal Fillers Used by Doctors?

Both injectables and fillers are something we often listen about. This blog focuses on the uses and differences between both. Also, we will take a look at how fillers and injectables work. Lastly, we will discuss some of the best fillers used by doctors. 

So, let’s get started with the main difference between the two. 

Botox and dermal fillers are cosmetic treatments that can be administered through injections. These are usually done in a doctor’s clinic. They are not invasive and do not require surgery.

Both treatments are popular. According to the American Society of Plastic Surgeons, 9 millions treatments were recorded in 2015. 

“Botox is made from purified bacteria, which freezes muscles. As a result, Botox can reduce the appearance of wrinkles and lines caused by facial expressions.”

“Fillers for the skin are ingredients that give fullness to areas that have lost their volume due to aging. The most common areas where wrinkles appear are around the lips, cheeks, and around your mouth.”

Let’s study both treatments separately to understand the difference better. 

What is Botox?

Botox is a purified version of botulinum toxins that have been extracted from bacteria. It is found in injectable form. Botox can be fatal in large quantities, but the small, controlled amount used to treat wrinkles has been safe for many decades.

Botox blocks nerve signals from the muscles it is injected into. The affected muscle becomes temporarily paralyzed or even frozen when these nerve signals are disrupted. However, certain wrinkles can be reduced or even eliminated if these muscles are not activated.

Botox and other botulinum-toxin treatments are often called neuromodulators or neurotoxins.

What Is Botox Suitable For?

Botox is only effective for wrinkles caused by muscle movement. These wrinkles are also known as “expression lines” and are sometimes called dynamic wrinkles.

Botox can treat most dynamic wrinkles on the upper face. These include the lines between the eyebrows and horizontal lines across the forehead. These lines can be caused by smiling, frowning, and squinting as well as other facial expressions.

Botox won’t treat wrinkles and fine lines caused by loss of plumpness or sagging in the face. These are called static wrinkles. These lines are found in the neck, cheeks, and jowl regions.

Botox is not an effective permanent treatment. For continued wrinkle-reducing results, repeated treatments are required. Botox’s muscle-relaxing effects last for about 3 to 4 months, according to most people.

Side Effects and Other Considerations for Botox

The ASPS considers Botox to be safe, and 6.7 million procedures were performed in 2015. Botox’s effects wear off over time, so most side effects are temporary.

Botox can cause side effects such as:

  • If the injection is near the eye, it may cause a drooping or sagging of the eyelids or brows.
  • Paralysis or weakness of nearby muscles
  • Dry mouth
  • Flu-like symptoms
  • Nausea
  • Trouble swallowing, speaking and breathing
  • Gallbladder problems
  • Vision problems or blurry vision

Antibodies that are created by the toxin may cause the treatment to fail. This happens in less than 1 percent of people who have repeated Botox treatments.

After Botox treatment, the ASPS recommends that you do not rub or massage the injection site. It could cause muscle drooping or other issues.

What Are Dermal Fillers?

Soft tissue fillers are also known as dermal fillers. They can be injected below the skin’s surface to increase volume and fullness. Dermal fillers are made up of:

  • Calcium hydroxylapatite, which is a mineral-like compound found in bones.
  • The skin’s plumpness is achieved by hyaluronic acid. It can be found in certain fluids and tissues.
  • Polyalkylimide is a transparent gel that can be used in conjunction with the body.
  • Polylactic acid, which stimulates the skin to make more collagen.
  • Polymethyl-methacrylate microspheres (PMMA), a semi-permanent filler

Each of these products is made to address different signs of aging and other cosmetic concerns. They can vary in terms of how long they work and the time it takes to get them there. For example, some fillers can last for six months while others may last two years. To determine the suitable filler for you, it is essential to discuss your individual needs with your doctor.

How Dermal Fillers Work?

Different types of dermal fillers can be used to treat various signs of aging. They may:

  • Reshape the thinning lips 
  • Fill in or enhance the shallow areas of the face.
  • Treat the shadows or wrinkles under the eyes caused by the lower eyelid.
  • Fill in or soften recessed scars.
  • Soften or fill in the static wrinkles on the lower part of the face.
  • Treat the wrinkles found around the mouth and on the cheeks. These wrinkles usually result from a loss of collagen and elasticity.

Considerations and Risks of Dermal Fillers

Although dermal fillers are generally considered safe, side effects can still occur. These are the most common side effects:

  • Itching, skin rash, or pimple-like eruptions
  • Redness, bleeding, swelling, or bruising
  • Unpleasing appearances include asymmetry, lumps, or overcorrection.
  • Skin damage that results in a wound, infection, or scarring
  • Feel the filler substance beneath the skin
  • Blindness and other vision problems
  • Loss of blood flow to the area can cause the death of skin cells

The Key Differences Between Fillers and Injectables

The differences between Botox injections and fillers can be summarized as follows:

Botox Injections: This will freeze muscles and stop wrinkles from forming due to facial expressions. These can be found on the forehead or around the eyes in the upper part of the face.

Dermal Fillers: These substances use hyaluronic acids and similar substances to “fill in” areas with lost volume or smoothness. This can be used to fill in wrinkles around your mouth, lips, and cheeks that are thin or have lost their fullness. These can also be used to smoothen forehead wrinkles and scars.

Some other factors about injectables and fillers are. 


  • Botox results can last up to four months. The results of dermal filler depending on the filler used.
  • Botox and fillers can sometimes be combined because they are different substances that have other uses. One example is Botox for correcting lines between the eyes and filler to correct smile lines.
  • Botox and fillers can be used safely, with side effects in less than 1% of recipients.


What Are the Three Main dermal Fillers Used by Doctors?

Juvederm, Restylane and Belotero are the most widely used dermal fillers. However, Radiesse and Sculptra are also very popular. Let’s find out what makes them so unique.


  • Juvederm


Juvederm is an injectable gel filler that is sold around the world. These fillers include Volbella, Ultra Plus, Voluma, and Ultra Smile. These injectables can correct superficial to severe facial wrinkles and thinning lips, and volume loss depending on their formulation. 

The effects may last for as long as 3 to 9 months. Your skin conditions and lifestyle will determine the longevity of your results. 


  • Restylane


Restylane is a nonanimal-based hyaluronic acid. It is used to correct a wide variety of aging problems. Fillers in this collection include Lyft, SubQ, Perlane, and Skinboosters Vital. These injectables can treat skin conditions such as volume loss, dull skin, skin depressions, fine lines, and deep wrinkles. 

Some formulations can also be used to augment the lips. These fillers can last up to 3 to 12 months depending on the issue being addressed, the filler used, your lifestyle, and your skin condition. 


  • Belotero


Belotero is a hyaluronic acid-based filler. Belotero injectables are obtained through bio fermentation. These cosmetic injectables are specially formulated to moisturize the skin, improve facial contours, smoothen out wrinkles and remove superficial to deep lines. 

Belotero, like Juvederm and Restylane, uses hyaluronic acids from non-animal sources and doesn’t require skin testing. The range includes five fillers

  • Soft
  • Hydro
  • Volume
  • Intense
  • Balance

Although the results can last for up to 6 months, depending on how long they are used, they can be prolonged.

Last Words

Each year, millions of Botox and Filler procedures are done. They have a strong safety record. Botox and fillers can be minimally invasive, but they come with risks. Therefore, it is crucial to be fully informed about all risks and benefits before undergoing these treatments.

Women who are pregnant or nursing should not use Botox or fillers. In addition, Botox and fillers should not be used if there are any medical conditions.

It is essential to discuss the benefits of Botox and fillers for your appearance. Though they can enhance a more youthful look, the results are typically not as powerful as having a surgical procedure, such as a facelift.

A qualified medical provider such as a dermatologist, plastic surgeon, or cosmetic surgeon will ensure that the procedure is performed safely and correctly. However, before making a final decision, it is important to discuss the provider’s experience in Botox and dermal fillers.